Francisco Ruiz (1476 – 23 October 1528) was a Roman Catholic prelate who served as Bishop of Ávila (1514–1528) and Bishop of Ciudad Rodrigo (1510–1514).
He was born in Toledo, Spain and ordained a priest in the Order of Friars Minor. On 18 November 1509 he was selected by the King of Spain and confirmed by Pope Julius II as Bishop of Ciudad Rodrigo.
