Wayne Stanley Kramer (né Kambes; April 30, 1948 – February 2, 2024) was an American musician, songwriter, producer, and film and television composer. Kramer came to prominence in the 1960s as the lead guitarist of the Detroit rock band MC5.
Kramer and guitarist Fred "Sonic" Smith co-founded the MC5 in 1963, with vocalist Rob Tyner, bassist Michael Davis, and drummer Dennis Thompson joining shortly after.